The 8 Best Pet-Safe Laundry Detergents In 2025 – Reviews And Guide

Last Updated on December 1, 2025 by Rachel Bennett

Choosing the right laundry detergent keeps your home fresh and safe for pets. Some detergents remove stains and odors without harming your furry friends.

Pets often leave behind stains and strong smells on clothes, bedding, and towels. Using regular detergents may irritate their skin or cause allergies. Pet-safe laundry detergents use gentle ingredients that clean well and protect pets’ health. Many contain enzymes that break down tough stains like urine, drool, or dirt.

They also eliminate odors instead of just masking them. Some options are fragrance-free or use natural plant-based formulas. This guide covers the best pet-safe detergents available for various needs. From heavy-duty cleaning to gentle care, these products help keep your home clean and your pets comfortable. Choose wisely to maintain a safe environment for everyone.

Bark2basics Dog-off Laundry Liquid Detergent

The Bark2Basics Dog-Off Laundry Liquid Detergent is perfect for pet owners, grooming salons, veterinary clinics, kennels, and pet resorts who need a powerful solution to eliminate tough pet odors and stains from clothes, towels, and apparel. If you frequently deal with stubborn pet-related messes and want a reliable, efficient detergent that maintains freshness, this product is designed for you.

Pros:

• Effectively eliminates pet odors and stains, leaving laundry fresh.
• Large 1-gallon size provides up to 128 loads, ideal for heavy use.
• Safe for various fabrics including clothes, towels, and grooming accessories.
• Natural color formula that is gentle yet powerful.
• Perfect for professional and household use in clinics, kennels, and grooming salons.

Cons:

• Bulk size may be less convenient for casual pet owners with limited storage space.
• May require pre-treatment for extremely stubborn stains.

The Bark2Basics Dog-Off Laundry Liquid Detergent is formulated to tackle the unique challenges of pet-related laundry. Its powerful cleaning agents penetrate deep into fibers to remove tough stains and neutralize odors, ensuring that your fabrics come out smelling fresh and looking clean. The natural color and gentle formula make it safe for repeated use on your pet’s belongings as well as your own apparel, reducing the risk of fabric damage.

With a capacity of 1 gallon and a remarkable 128 loads per container, this detergent offers excellent value for businesses and busy pet owners alike. Whether you operate a kennel or simply have multiple pets at home, it handles large laundry loads efficiently, minimizing the need for frequent repurchase. Its versatility across different fabrics and settings makes it a dependable choice for maintaining hygiene and freshness in pet environments.

To buy this product, click here.

Pet Laundry Detergent Odor Remover

The Pet Laundry Detergent Odor Remover by ACTIVE is perfect for pet owners who struggle with persistent pet odors and stains. If you have dogs or cats that frequently soil their bedding or leave behind stubborn smells, this enzyme-based powder detergent is designed for you. It’s ideal for anyone looking to maintain a fresh and clean environment without resorting to harsh chemicals.

Pros:

• Enzyme-based formula effectively breaks down odors and stains.
• Compatible with HE washers, ensuring energy-efficient cleaning.
• Handles a variety of issues, including urine, smell, dog drool, and stains.
• Offers up to 64 loads, providing long-lasting use.

Cons:

• The 2.0-pound weight may be cumbersome for some users.
• Some consumers may prefer a liquid detergent over a powder form.

The ACTIVE Pet Laundry Detergent stands out due to its natural enzymatic deodorizing properties. These enzymes are crucial as they target and break down organic matter, which is the root cause of unpleasant pet odors. This means that rather than masking smells, the detergent eliminates them at the source, leaving your pet’s bedding smelling fresh and clean.

Moreover, its compatibility with HE washers makes it a practical choice for those who are conscious of energy consumption. The detergent is also versatile enough to tackle a variety of common pet-related laundry issues, from cat pee to dog drool, ensuring your laundry comes out spotless. With the capacity to handle 64 loads, it’s a cost-effective solution for pet owners seeking to maintain a clean and odor-free home environment.

To buy this product, click here.

Pet Parents® Pettergent®

Ideal for pet owners who want a specialized solution to keep their laundry fresh and clean, the Pet Parents® PetTergent® Enzymatic Pet Laundry Detergent is perfect for those dealing with pet stains and odors. If you have dogs, cats, or other furry friends that often leave messes on clothes, bedding, or other washable items, this detergent offers targeted cleaning power designed specifically for pet-related laundry challenges.

Pros:

• Formulated with enzymes to effectively break down and remove pet stains and odors.
• Includes a calming scent that helps maintain a fresh, pleasant environment.
• Compact 32 oz bottle provides up to 32 loads, making it cost-effective.
• Safe for use on a variety of fabrics and washable pet items.
• Designed specifically for pet parents, ensuring targeted cleaning without harsh chemicals.

Cons:

• May be priced higher than regular laundry detergents.
• Limited availability compared to mainstream detergent brands.
• Some users might prefer unscented options for sensitive pets.

The Pet Parents® PetTergent® stands out due to its enzymatic formula, which effectively tackles tough pet stains like urine, feces, and dirt. Unlike regular detergents, its enzymes actively break down organic matter, ensuring a deeper clean and eliminating lingering odors that typical detergents might leave behind. This means your laundry not only looks clean but also smells fresh, creating a more pleasant living space for both you and your pets.

Additionally, the detergent’s calming scent adds an extra layer of comfort, which can be especially beneficial for anxious pets or busy households. The 32 oz bottle size delivering 32 loads strikes a balance between convenience and long-term use, making it ideal for regular pet laundry needs. Its thoughtful design caters to the unique challenges faced by pet owners, ensuring your clothes, pet bedding, and other washable items remain clean, fresh, and odor-free.

To buy this product, click here.

Laundrapet 3x Strength Premium Laundry Detergent

The LaundraPet 3X Strength Premium Laundry Detergent with Enzyme Cleaner is ideal for pet owners who want a powerful solution to eliminate stubborn pet stains and odors from their laundry. If you are looking for a detergent that not only cleans but also targets organic stains caused by pets, this enzymatic detergent by Alpha Tech Pet is designed specifically for you. It is perfect for households with multiple pets or for anyone seeking a deep clean that protects fabrics while removing tough pet-related messes.

Pros:

• Powerful enzyme-based formula that breaks down tough pet stains and odors effectively
• Large 64 oz bottle provides up to 96 washes, offering great value for money
• Safe for use on a variety of fabrics, including pet bedding and clothing
• Manufactured by Alpha Tech Pet, a trusted brand in pet stain removal
• Compact size with convenient dimensions (9.5 x 6.0 x 3.0 inches) and manageable weight (4.0 pounds)

Cons:

• Specialized formula may be pricier than standard laundry detergents
• Primarily targeted at pet stains, may not be as effective on non-pet related stains
• Requires proper dosing to avoid residue build-up in washing machines

The LaundraPet 3X Strength Premium Laundry Detergent is formulated with powerful enzymes that specifically target organic materials such as urine, feces, and other pet-related stains. This enzymatic action breaks down proteins and odors at the molecular level, ensuring a deep clean that standard detergents often cannot achieve. Users benefit from fresher, cleaner laundry that maintains fabric integrity without harsh chemicals.

Additionally, the detergent’s concentrated formula means a small amount goes a long way, making it economical despite its premium pricing. Its versatility allows safe use on various textiles, including delicate pet bedding and everyday clothing, which means pet owners do not have to compromise on fabric care while tackling stubborn stains. Overall, this product offers a reliable and efficient cleaning solution tailored to the needs of pet-loving households.

To buy this product, click here.

Bark2basics Dog-off Laundry Liquid Detergent

The Bark2Basics Dog-Off Laundry Liquid Detergent is perfect for pet owners, grooming salons, clinics, kennels, and resorts who need an effective solution to eliminate stubborn pet odors and stains from clothes, towels, and apparel. If you are looking for a reliable detergent that specifically targets pet-related messes while being gentle on fabrics, this product is an ideal choice.

Pros:

• Effectively eliminates pet odors and stains, keeping laundry fresh and clean.
• Large 1 gallon size provides up to 128 loads, offering great value for frequent use.
• Safe and suitable for various fabrics including clothes, towels, and apparel.
• Ideal for professional use in grooming salons, clinics, kennels, and resorts.
• Natural color formulation that is gentle and environmentally friendly.

Cons:

• Heavier weight at 8 pounds might be less convenient for some users to handle.
• Specific to pet-related laundry, may not be as versatile for other household laundry needs.

The Bark2Basics Dog-Off Laundry Liquid Detergent is designed to tackle the unique challenges of pet laundry by targeting both odors and stains that regular detergents often struggle to remove. Its powerful formula ensures that even the most persistent pet smells are neutralized, leaving your garments and linens smelling fresh. The large 1 gallon bottle size means you can enjoy long-lasting use without frequent repurchasing, making it economical for both personal and professional settings.

Additionally, this detergent’s gentle yet effective composition ensures that it is safe for a variety of fabrics, maintaining the quality of your clothes, towels, and other apparel after repeated washes. The product’s natural color and carefully crafted formula make it a smart choice for environmentally conscious consumers and businesses alike. Whether you operate a grooming salon or simply want the best care for your pet’s laundry at home, Bark2Basics Dog-Off offers a specialized cleaning solution that meets these needs.

To buy this product, click here.

Biokleen Natural Laundry Detergent Liquid

The Biokleen Natural Laundry Detergent Liquid is ideal for environmentally conscious consumers who prioritize using safe, non-toxic cleaning products. This detergent is perfect for families with young children and pets, as it contains no artificial colors or preservatives, ensuring a gentle yet effective clean. Those looking for a powerful, eco-friendly alternative to traditional laundry detergents will find this product especially beneficial.

Pros:

• Contains plant-based, concentrated formula that is gentle on fabrics and skin.
• Suitable for up to 300 loads, offering great value for money.
• Eco-friendly and biodegradable, reducing environmental impact.
• Free from artificial colors and preservatives, making it safe for kids and pets.
• Has a refreshing Citrus Essence scent that leaves clothes smelling clean and fresh.

Cons:

• May be slightly more expensive compared to conventional detergents.
• Some users might find the scent too mild compared to synthetic fragrances.
• Requires careful dosing due to its concentrated formula.

The Biokleen Natural Laundry Detergent Liquid stands out for its commitment to sustainability and safety. Its plant-based ingredients not only clean effectively but also reduce the risk of allergic reactions and skin irritation, which is crucial for households with sensitive members. The detergent’s concentration means that a small amount goes a long way, making it economical in the long run despite a higher upfront cost.

Additionally, the detergent’s eco-friendly formula ensures that it breaks down naturally without harming aquatic life or polluting waterways. The refreshing Citrus Essence adds a pleasant, natural fragrance to your laundry without relying on harsh chemicals. Overall, this product combines effectiveness, safety, and environmental responsibility, making it a smart choice for modern, conscientious consumers.

To buy this product, click here.

Febreze Laundry Detergent Additive For Pet Supplies

The Febreze Laundry Detergent Additive for Pet Supplies is ideal for pet owners who struggle with persistent pet odors in their fabrics and clothing. If you want a reliable solution that effectively removes tough pet smells with ease, this product is designed specifically for you. It’s perfect for households with dogs, cats, or any pets that leave behind stubborn odors after playtime or outdoor activities.

Pros:

• Maximum Strength In Wash Pet Odor Eliminator that works in a single wash
• Leaves a fresh scent on fabrics and clothing
• Large 98 fl oz size provides long-lasting use
• Compatible with most laundry detergents and washing machines
• Designed to remove tough odors specifically from pet-related stains and smells

Cons:

• Relatively heavy at 7 pounds, which may be cumbersome for some users
• No added color or fragrance options beyond the fresh scent
• May require multiple treatments for extremely strong or old odors

The Febreze Laundry Detergent Additive offers powerful odor elimination by targeting the root cause of pet smells embedded in fabrics. Its formula is engineered to break down and neutralize odors during the wash cycle, ensuring that clothing and linens come out smelling clean and fresh. This additive works seamlessly alongside your regular detergent without compromising cleaning performance.

With a generous 98 fl oz size, this product provides great value and convenience for frequent use, especially in homes with multiple pets. The fresh scent adds an extra layer of cleanliness without being overpowering, making it suitable for sensitive noses. Overall, this Febreze additive is a practical choice for anyone looking to maintain a fresh-smelling home despite the challenges of pet odors.

To buy this product, click here.

Seventh Generation Concentrated Laundry Detergent Liquid

The Seventh Generation Concentrated Laundry Detergent Liquid Free & Clear Fragrance Free 40 oz. is ideal for individuals and families who prioritize using a natural, eco-friendly product that is gentle on sensitive skin. It is especially suitable for those who prefer a fragrance-free detergent free from dyes and artificial scents, making it perfect for people with allergies, skin sensitivities, or those who want a more sustainable laundry solution.

Pros:

• Made by trusted brand Seventh Generation, ensuring product quality and eco-conscious manufacturing.
• Fragrance-free formula reduces risk of irritation for sensitive skin and allergies.
• Concentrated formula means less detergent per load, providing more washes per bottle and better value.
• Free from dyes and artificial additives, promoting a natural and gentle cleaning process.
• Biodegradable ingredients support environmental sustainability.

Cons:

• May not provide a strong scent for those who prefer fragranced detergents.
• Price point can be higher compared to conventional detergents.
• Some users may find it less effective on heavily soiled or greasy stains.

The Seventh Generation Concentrated Laundry Detergent Liquid Free & Clear stands out due to its commitment to both user health and the environment. Its concentrated formula ensures that you use less product per load without compromising cleaning power, which is not only cost-effective but also reduces plastic waste over time. Being fragrance-free and free from dyes, this detergent is particularly beneficial for individuals with sensitive skin or allergies, providing a gentle yet effective clean.

Additionally, the detergent’s biodegradable ingredients and ethical manufacturing by Unilever under the Seventh Generation brand make it an excellent choice for eco-conscious consumers. Its balanced cleaning ability removes everyday dirt and stains while maintaining fabric care, making it suitable for various laundry needs. Though it may not tackle extremely tough stains as aggressively as some chemical-heavy detergents, its natural composition offers a healthier alternative for your laundry routine.

To buy this product, click here.

Frequently Asked Questions

What Makes A Laundry Detergent Pet-safe?

Pet-safe detergents use natural, non-toxic ingredients that don’t harm pets. They avoid harsh chemicals, fragrances, and dyes that irritate skin or cause allergies. These detergents effectively remove pet odors and stains while ensuring your furry friends stay safe and comfortable around cleaned fabrics.

How Do Enzymatic Detergents Remove Pet Stains?

Enzymatic detergents break down proteins, fats, and oils in pet stains. This action targets urine, drool, and feces to eliminate odors and discoloration. They are highly effective for tough pet stains, ensuring clothes and bedding look fresh and hygienic after washing.

Can Pet-safe Detergents Be Used In He Washers?

Yes, many pet-safe detergents like Bark2Basics and Alpha Tech Pet are HE washer compatible. They produce low suds and rinse out easily, protecting your washer and ensuring thorough cleaning. Always check the label for HE compatibility to maximize cleaning efficiency.

Are Fragrance-free Detergents Better For Pets?

Fragrance-free detergents like Seventh Generation reduce the risk of skin irritation and allergies in pets. They contain no artificial perfumes or dyes, making them ideal for sensitive pets. These detergents clean effectively without causing discomfort or respiratory issues.

How Often Should I Wash Pet Bedding With Detergent?

Wash pet bedding weekly with a pet-safe detergent to reduce odors, bacteria, and allergens. Regular cleaning keeps your pet’s sleeping area fresh and healthy. Using enzymatic detergents removes tough stains and odors, ensuring a hygienic environment for your pets.

Conclusion

Choosing the right pet-safe laundry detergent keeps your home fresh and your pets healthy. These detergents gently remove odors, stains, and dirt without harsh chemicals. Many use natural enzymes to break down pet messes effectively. They work well for pet beds, clothes, towels, and more.

Safe formulas mean less risk of skin irritation for pets and family members. Plus, these options suit different washing machines and preferences, including fragrance-free choices. Regular use helps maintain clean fabrics and a pleasant-smelling home. Remember, a good detergent supports both cleanliness and pet safety.

Try to pick one that fits your needs and washing habits. Clean laundry, happy pets, and peace of mind. What could be better?